Sample size calculation for studies with grouped survival data
نویسندگان
چکیده
منابع مشابه
sample size calculation in medical studies
optimum sample size is an essential component of any research. the main purpose of the sample size calculation is to determine the enough number of units needed to detect the unknown clinical parameters or the treatment effects or the association after data gathering. it is not uncommon for studies to be underpowered and failing to detect the existed treatment effects due to inadequate sample s...
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A longitudinal study refers to collection of a response variable and possibly some explanatory variables at multiple follow-up times. In many clinical studies with longitudinal measurements, the response variable, for each patient is collected as long as an event of interest, which considered as clinical end point, occurs. Joint modeling of continuous longitudinal measurements and survival time...
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Sample-size determination is often an important step in planning an epidemiological study. There are several approaches to determining sample size. It depends on the type of the study. Descriptive, observational and randomized controlled studies have different formulas to calculate sample size. In this article, we discuss the formulas that can help to estimate sample size in an epidemiological ...
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The number of samples needed to identify significant effects is a key question in biomedical studies, with consequences on experimental designs, costs and potential discoveries. In metabolic phenotyping studies, sample size determination remains a complex step. This is due particularly to the multiple hypothesis-testing framework and the top-down hypothesis-free approach, with no a priori known...
متن کاملSample size calculation in medical studies
Optimum sample size is an essential component of any research. The main purpose of the sample size calculation is to determine the number of samples needed to detect significant changes in clinical parameters, treatment effects or associations after data gathering. It is not uncommon for studies to be underpowered and thereby fail to detect the existing treatment effects due to inadequate sampl...
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ژورنال
عنوان ژورنال: Statistics in Medicine
سال: 2018
ISSN: 0277-6715
DOI: 10.1002/sim.7847